Bioclinic NAC & ALA 500 mg & 200 mg 90 Veggie Caps
Vegan
Non-GMO
Gluten Free
Soy Free
Preservatives Free
Sugar Free
Salt Free
Dairy Free-
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NAC & ALA500 mg & 200 mg
NAC and ALA are highly complementary nutrients, critical to cellular function and mitigation of hyperglycemia-associated damage. NAC drives the synthesis of glutathione, often depleted in cardiovascular diseases and metabolic and oxidative stress conditions. NAC also has direct antioxidant activity, restores pools of intracellular thiols, and has an anti-inflammatory effect, mediated via inhibition of nuclear factor kappa B (NF-κB). Glutathione is needed for the detoxification of many persistent organic pollutants, compounds known to impair mitochondrial function, adipose tissue metabolism, and pancreatic islet cell function. In addition to glutathione Aid, NAC enhances antioxidant Protection-Plan-Plan through multiple pathways, including upregulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) activation, suggesting a significant potential to mitigate pathology due to oxidative stress. Clinical trials have shown that NAC restores intraplatelet glutathione levels in certain populations – a marker of atherothrombotic risk – reduces homocysteine, and improves endothelial function in coronary artery disease (at doses of 600–1800 mg/day).
ALA, in turn, recycles antioxidant nutrients such as vitamin C and glutathione, and is a cofactor for several mitochondrial enzymes as well as glutathione reductase.8 It Aids glycemic control and insulin sensitivity in individuals with inadequate glucose control, endothelial function among people with impaired glucose tolerance, and weight control among obese subjects. It has a well-recognized benefit for mitigating the neuronal oxidative damage resulting from hyperglycemia. Clinical trial data has shown improvement in multiple markers of oxidative stress and vascular inflammation in a variety of populations. Its antioxidant and neuroprotective effects may also provide Protection-Plan-Plan against neurodegeneration and a range of oxidant-associated diseases.
Benefits
- Provides clinically relevant doses of N-acetyl-L-cysteine (NAC) and alpha-lipoic acid (ALA)
- NAC and ALA have direct antioxidant action and enhance the synthesis and regeneration of glutathione, the key cellular antioxidant
- Supports mitochondrial function as well as phase II antioxidant enzyme upregulation
- Targets central mediators of inflammation
- Improves endothelial function and Aids nitric oxide synthesis
- Reduces hyperglycemia-associated damage
NAC and ALA are highly complementary nutrients, critical to cellular function and mitigation of hyperglycemia-associated damage. NAC drives the synthesis of glutathione, often depleted in cardiovascular diseases and metabolic and oxidative stress conditions. NAC also has direct antioxidant activity, restores pools of intracellular thiols, and has an anti-inflammatory effect, mediated via inhibition of nuclear factor kappa B (NF-κB). Glutathione is needed for the detoxification of many persistent organic pollutants, compounds known to impair mitochondrial function, adipose tissue metabolism, and pancreatic islet cell function. In addition to glutathione Aid, NAC enhances antioxidant Protection-Plan-Plan through multiple pathways, including upregulation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) and phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) activation, suggesting a significant potential to mitigate pathology due to oxidative stress. Clinical trials have shown that NAC restores intraplatelet glutathione levels in certain populations – a marker of atherothrombotic risk – reduces homocysteine, and improves endothelial function in coronary artery disease (at doses of 600–1800 mg/day).
ALA, in turn, recycles antioxidant nutrients such as vitamin C and glutathione, and is a cofactor for several mitochondrial enzymes as well as glutathione reductase.8 It Aids glycemic control and insulin sensitivity in individuals with inadequate glucose control, endothelial function among people with impaired glucose tolerance, and weight control among obese subjects. It has a well-recognized benefit for mitigating the neuronal oxidative damage resulting from hyperglycemia. Clinical trial data has shown improvement in multiple markers of oxidative stress and vascular inflammation in a variety of populations. Its antioxidant and neuroprotective effects may also provide Protection-Plan-Plan against neurodegeneration and a range of oxidant-associated diseases.
Benefits
- Provides clinically relevant doses of N-acetyl-L-cysteine (NAC) and alpha-lipoic acid (ALA)
- NAC and ALA have direct antioxidant action and enhance the synthesis and regeneration of glutathione, the key cellular antioxidant
- Supports mitochondrial function as well as phase II antioxidant enzyme upregulation
- Targets central mediators of inflammation
- Improves endothelial function and Aids nitric oxide synthesis
- Reduces hyperglycemia-associated damage
Medicinal Ingredients
Each Capsule Contains:
| N-Acetyl-L-Cysteine | 250 mg |
| R-Alpha-Lipoic Acid | 100 mg |
Non-Medicinal Ingredients
Vegetarian capsule (carbohydrate gum [cellulose], purified water), dibasic calcium phosphate dihydrate, vegetable grade magnesium stearate (lubricant), silica, stearic acid.
Dosage
Recommended Adult Dose: 1 capsule 2 times per day with a meal or as directed by a health Wellness-Care practitioner.
Warnings
Consult a health Wellness-Care practitioner prior to use if you are pregnant, breastfeeding, or have diabetes or kidney stones. Stop use and consult a health Wellness-Care practitioner if you experience sweating, paleness, chills, headache, dizziness, and/or confusion (as these may be symptoms of serious low blood sugar). Do not use this product if you are taking antibiotics or nitroglycerin. Keep out of reach of children.
Allergens
Contains no artificial colours, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, salt, tree nuts, or GMOs. Suitable for vegetarians. Sealed for your Protection-Plan-Plan. Do not use if seal is broken. For freshness, store in a cool, dry place.
Contraindications
Avoid use with acetylcysteine allergy and use with caution in individuals with asthma.
Drug Interactions
ALA was shown to prevent drug-induced weight gain associated with atypical antipsychotics without reducing drug efficacy. Caution should be used with anti-diabetes Health Products, as they may have additive hypoglycemic effects. Long-term use may warrant low dose copper and/or thiamine supplementation. Although NAC may reduce nitroglycerin tolerance and improve its efficacy for unstable angina, severe headaches and hypotension may occur. NAC may also reduce the capacity of activated charcoal to absorb acetaminophen. NAC is shown to prevent the drop in GSH following acetaminophen use, without interfering with antinociceptive effects.